Complementing Yeast rho1 Mutation Groups with Distinct Functional Defects

Functional specialization of the yeast Rho1 GTP exchange factors

Complementing Model Learning with Mutation-Based Fuzzing

An ongoing challenge for learning algorithms formulated in the Minimally Adequate Teacher framework is to efficiently obtain counterexamples. In this paper we compare and combine conformance testing and mutation-based fuzzing methods for obtaining counterexamples when learning finite state machine models for the reactive software systems of the Rigorous Exampination of Reactive Systems (RERS) c...

Distinct roles of Rho1, Cdc42, and Cyk3 in septum formation and abscission during yeast cytokinesis

In yeast and animal cytokinesis, the small guanosine triphosphatase (GTPase) Rho1/RhoA has an established role in formation of the contractile actomyosin ring, but its role, if any, during cleavage-furrow ingression and abscission is poorly understood. Through genetic screens in yeast, we found that either activation of Rho1 or inactivation of another small GTPase, Cdc42, promoted secondary sep...

Negative functional interaction between cell integrity MAPK pathway and Rho1 GTPase in fission yeast.

Rho1 GTPase is the main activator of cell wall glucan biosynthesis and regulates actin cytoskeleton in fungi, including Schizosaccharomyces pombe. We have obtained a fission yeast thermosensitive mutant strain carrying the rho1-596 allele, which displays reduced Rho1 GTPase activity. This strain has severe cell wall defects and a thermosensitive growth, which is partially suppressed by osmotic ...

COUNTING DISTINCT FUZZY SUBGROUPS OF SOME RANK-3 ABELIAN GROUPS

In this paper we classify fuzzy subgroups of a rank-3 abelian group $G = mathbb{Z}_{p^n} + mathbb{Z}_p + mathbb{Z}_p$ for any fixed prime $p$ and any positive integer $n$, using a natural equivalence relation given in cite{mur:01}. We present and prove explicit polynomial formulae for the number of (i) subgroups, (ii) maximal chains of subgroups, (iii) distinct fuzzy subgroups, (iv) non-isomorp...